2 edition of Proteins and nucleic acids; structure and function. found in the catalog.
Proteins and nucleic acids; structure and function.
Max F. Perutz
|Series||Weizmann memorial lectures, 1961|
|The Physical Object|
|Pagination||x, 211 p. illus. ;|
|Number of Pages||211|
Description The Biochemistry of Plants: A Comprehensive Treatise, Volume 6: Proteins and Nucleic Acids provides information pertinent to the nucleic acids and the regulation of the expression of this information. Free Shipping No minimum order. New insights are now being gained from comparative studies only recently made possible due to the size of the database, as well as from careful biochemical and biophysical studies. The nucleobases are joined to the sugars via an N-glycosidic linkage involving a nucleobase ring nitrogen N-1 for pyrimidines and N-9 for purines and the 1' carbon of the pentose sugar ring. Anne Marie Helmenstine, Ph.
Molecular composition and size[ edit ] Nucleic acids are generally very large molecules. Amino acids are made up mostly of the elements carbon, hydrogen, nitrogen, and oxygen, but they may also contain sulfur. The genetic code The identification of each group of three nucleotides and its particular amino acid. They are bicyclic molecules, which means they consist of two rings. This text then examines the enzymes involved in the cleavage and degradation of DNA. What is produced in transcription?
Nucleotides are composed of a nitrogenous base, a five-carbon sugar, and a phosphate group. The text is supported by an extensive list of references, making it a definitive reference source. The bases bond to each other in a very specific way. Each molecule of messenger RNA mRNA is a transcribed copy of a gene that is used by a cell for synthesizing a polypeptide chain.
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The major relationship between the two has to do with protein production -- DNA contains the information that a cell uses, with the help of RNA, to make protein. Protein denaturation may result in loss of function, and loss of native state. The mRNA formed in the nucleus during transcription is transported across the nuclear membrane into the cytoplasm to the ribosomes—carrying with it the genetic instructions.
Further experimentation threw much light on the nature of the genetic code, as follows: The code is virtually universal; animal, plant, and bacterial cells use the same codons to specify each amino acid with a few exceptions.
Two examples of nucleic acids include deoxyribonucleic acid better known as DNA and ribonucleic acid better known as RNA.
DNA contains sections called genes, which encode the body's genetic information. Other nucleic acids, various types of RNA, assist in the protein-production process.
What is the fate of each strand of the parent DNA double helix? Having trained in the labs of Profs. Description The Biochemistry of Plants: A Comprehensive Treatise, Volume 6: Proteins and Nucleic Acids provides information pertinent to the nucleic acids and the regulation of the expression of this information.
Interestingly, some nucleotides perform important cellular functions as "individual" molecules, the most common example being adenosine triphosphate or ATPwhich provides energy for many cell functions.
Nucleic Acid Monomers Nucleotides are composed of a nitrogenous base, a five-carbon sugar, and a phosphate group. Conformational ensembles have been devised as a way to provide a more accurate and 'dynamic' representation of the conformational state of intrinsically disordered proteins.
For more information on sequences, see Section The book also emphasises the impact of structural biology on understanding how proteins interact with nucleic acids and it is intended for advanced students and established scientists wishing to broaden their horizons. Each individual three-nucleotide coding unit, as we have seen, is called a codon.
High-resolution structures of protein-RNA complexes were relatively rare until the last decade. About this title The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved.
What is the sequence of complementary template strand? One easy way to remember which bases pair with each other is to look at the shape of the letters. A pyrimidine bases consists of a single ring or heterocyclic amine. When a cell divides, a copy of this genetic code is passed to the new cell.
One reason for the iconic nature of this structure is the elegant explanations it provides for DNA metabolism. Key chapters are devoted to the chemical synthesis of nucleosides and nucleotides, oligonucleotides and their analogues and to analytical techniques applied to nucleic acids.
All other amino acids have two or more codons. Other chapters provide a critical assessment of eukaryotic nucleic acid polymerases. With the fundamentals laid out, discussion turns to more specialized examples taken from important aspects of nucleic acid metabolism. Both halves are illustrated with important real life examples.
Here we have a code that is extensive enough to direct the synthesis of the primary structure of a protein molecule. Instead, current review articles tend to focus on particular subtopics of interest.
Adenine, guanine, and thymine are called the purine bases.DNA and RNA structure and function. Nucleotides and polynucleotides.
mRNA, rRNA, tRNA, miRNA, and siRNA. If you're seeing this message, it means we're having trouble loading external resources on our website. Nucleic acids. This is the currently selected item. Practice: Central dogma. The polymers of carbohydrates, proteins, and nucleic acids are built from three different types of monomers: monosaccharides, amino acids, and nucleotides, respectively.
Compare the composition, structure, and function of starch and cellulose. About this book. The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently.
Nucleic Acids Nucleic acids are key macromolecules in the continuity of life. They carry the genetic blueprint of a cell and carry instructions for the functioning of the cell.
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material found in all living organisms, ranging from. Oct 14, · Honors Biology - Introduction to proteins, their structure and function. Honors Biology - Introduction to proteins, their structure and function Ch.
2B - Nucleic Acids - Duration: Start studying Biology - Chapter 2 - Carbohydrates, Lipids, Nucleic Acids, Proteins. Learn vocabulary, terms, and more with flashcards, games, and other study tools.